In recent years, domestic scholars have conducted a lot of researches on the pharmacological effects of Buyang Huanwu Decoction(BYHWD) against the cerebral ischemia. The results showed that BYHWD could regulate cerebral hemodynamics factors, it was anti-inflammatory, against free radicals, and could protect the blood-brain barrier and neurons against the cerebral ischemic injury. This paper reviewed the pharmacological mechanism of BYHWD in treatment of ischemic stroke.