To analyze retrospectively the medications for leukopenia after radio-chemotherapy in cancer treated in recent decade years so as to provide the evidence and approaches to the application of Chinese medicine in clinic.Methods:The literatures on Chinese medicine formulas were collected from Chinese Journal Full-text Database and Chinese Biological Medicine on Disc and Wanfang Database in terms of the treatment of leukopenia after radio-chemotherapy in cancer with traditional Chinese medicine or integrated Chinese and western medicine from year 2004 to 2013. In reference to the standard terminology in Pharmacopoeia of the Peoples Republic of Chinese and Chinese Materia mMdica, using SPSS13.0 statistical software, the usage frequency of single herb, drug efficacy and nature, flavor and channel tropism of Chinese herbs were classified and analyzed statistically.Results:One hundred and three relevant literatures were retrieved, among which, there were 114 Chinese herbal formulas, 148 different herbs and 18 categories of Chinese herbal medicine. The total frequency of single herb was 1229 times. Among those different herbs, 66.4% of them were in the category of replenishing the deficiency, 7.16% of them were of activating blood circulation and resolving stasis and 5.04% of them were of promoting digestion. Astragalus membranaceus was on the top in usage frequency, totally 91 times, accounting for 79.8%. Regarding the nature of Chinese herbal medicine, the warm, neutral and cold natures were predominated, in which, those of warm nature accounted for 52.5%. Regarding to the flavor, sweet, bitter and pungent flavors were predominated, in which, those of sweet flavor accounted for 52.7%. Regarding to channel tropism, spleen, liver and kidney channels were mainly involved.Conclusion:In the treatment of leukopenia after radio-chemotherapy in cancer, strengthening the antipathogenic qi is the root, also it requires focusing on tonifying qi and blood, and regulating the functions of spleen, liver and kidney. Astragalus membranaceus is the common herb in the entire process of treatment.