Internationally, there was no consensus on the best approach for gait analysis in patients with osteoarthritis (OA) of the knee. Although there is lack of standardization, it is consistently demonstrated that osteoarthritis patients may exhibit different gait parameters according to the disease stage. Methods:This summary reviews recent studies that have been undertaken to explore the manner for measure the characteristic on osteoarthritis, and clarify how the variability of gait parameters is influenced by the morbidity of KOA.Results:Twenty two studies were included, among which six were contrapose kinematics parameter, six were contrapose kinetic parameter, four were EMG analysis, and six were about the gait analysis in treatment effect.Conclusion:3DGA as a new biological mechanics analysis method has widely used in the study of many diseases. Based on the uncertainty of the pathogenic mechanism of KOA, diagnosis and treatment are lack of a quantitative criteria of absolute authority. This will not benefit the systematic KOA diagnosis as well as the quantity of severity of its definition.