Abstract:Using evidence-based medicine system to make an impersonal evaluation on the validity of Chinese medicine in the treatment of hyperuricemia. Methods: Randomized controlled trials(RCT) on Chinese medicines efficacy on treating hyperruricemia were retrieved from domestic medicinal journals (1980-2014) and then were evaluated through meta-analysis. Results: Ten studies involved 1000 patients were identified. The results showed that there was significant difference between using Chinese medicine and routine chemical to treat hyperruricemia: (P=0.16, [OR=2.58, 95%CI (1.58, 4.21)]). The meta-analysis result of reducing the level of blood uric acid was [SMD=SMD=-0.58, 95%CI(-0.90,-0.26), Z=3.53, (P=0.0004)]. The differences between treatment group and control group were of statistical significance. Conclusion: In both the aspects of total clinical efficacy and blood uric acid level reduction, the performance of treatment groups (using Chinese medicine) was better than the control groups (using chemical drugs). However, because some of the RCTs reviewed in this study did not fulfill the strict requirement of evidence-based medicine, the results of this study can have deviation. Therefore, more qualified research with large sample were expected to evaluate these results.