To explore the distribution regularities of traditional chinese medicine syndromes by collecting ten units nationwide clinical data of chronic hepatitis B (ALT≥2ULN) patients. Methods: By using the methods of frequency and factor analysis to research the traditional Chinese medicine syndromes of 1 003 cases chronic hepatitis B(ALT≥2ULN) patients. Results: By analyzing the clinical data of 1 003 cases chronic hepatitis B(ALT≥2ULN) patients, 21 common factors related to syndromes were obtained. Conclusion: The main syndromes of chronic hepatitis B(ALT≥2ULN) patients are:1)liver stagnation and spleen deficiency;2)damp heat in the liver and gallbladder;3)stagnancy of stomach;4)spleen deficiency and dampness;5)liver and kidney yin deficiency;6)liver blood stasis;7)dampness-heat obstructing the center;8)incoordination between the liver and stomach.