To observe the clinical efficacy of syndrome essence differentiation based treatment in chronic heart failure(CHF) and the improvement in LVEF value， 6MWT and life quality of patients.Methods：Patients with chronic heart failure of 55 cases were randomly divided into two groups： treatment group and control group， both groups were given conventional western medicine treatment while the treatment group were also given Chinese medicine treatment based on Chinese medicine syndrome essence differentiation. Then the Chinese medicine symptom(TCM)， LVEF， 6MWT and quality of life were observed. Results： Clinical total effective rate of the two groups were not significant different， for treatment group， it was 66.67% and control group 72% (P>0.05). LVEF， 6MWT and the quality of life were promoted in each group with significant differences (P<0.05)， but without statistic significances between two groups(P>0.05). Conclusion： It needs further study to figure out the treatment based on syndrome differentiation in improving Chinese medicine symptoms， LVEF and the quality of life.