To observe and compare the clinical effects of three treating groups: Jinkui Shenqi Pill with abdominal acupuncture, Jinkui Shenqi Pill alone, intermittent catheterization in the treatment of kidney qi deficiency neurogenic bladder. Methods: This study adopted multi-center, randomized controlled clinical trials, in which 138 kidney qi deficiency neurogenic bladder patients were randomly divided into three groups, including the Jinkui Shenqi Pill group, the intermittent catheterization group and the Jinkui Shenqi Pill combined with abdominal acupuncture group. Each group received a continuous treatment for three periods. Results: Compared with the groups of the intermittent catheterization and Jinkui Shenqi Pill group, the combination therapy of Jinkui Shenqi Pill and acupuncture significantly reduced the score of patient’s QOL (P<0.05), and the volume of bladder residual urine (P<0.05) and at the same time increase the maximal urinary flow rate (P<0.05). Regarding the comprehensive evaluation of the curative effect, the total effective rate was 91.21% in the Jinkui Shenqi Pill combined with abdominal acupuncture group, better than the intermittent catheterization group and the Jinkui Shenqi Pill group. Conclusion: The therapy for the of kidney qi deficiency neurogenic bladder by Jinkui Shenqi Pill combined with abdominal acupuncture has obviously better curative effect than the treatment of intermittent catheterization and Jinkui Shenqi Pill alone. This combined therapy of acupuncture and Chinese medicine can be simply performed, economical and practical, with little pain and sustainable effects, and therefore is convenient for clinical promotion.