中西医结合治疗急性脑出血的临床研究——中医中风病诊疗规范研究之二
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浙江省中医药科技计划项目——“中医中风病诊疗规范研究”(编号:20090690096)


Clinical Study on Integrative Medicine of Acute Cerebral Hemorrhage
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    摘要:

    目的:通过系列临床研究,体现我科中医药治疗急性脑出血的独特临床优势,并验证我科中医中风病诊疗方案的科学性、实用性、可重复性及可操作性。方法:将120例急性脑出血患者随机分为西医治疗组和中西医结合治疗组。通过对治疗前后血超氧化物歧化酶(Superoxide Dismutase,SOD)、脂质过氧化物血清丙二醛(MDA)、C反应蛋白(C-reactiVe Protein,CRP)、同型半胱氨酸(Homocysteine,HCY)指标的比较,分析比较2组患者之间在近期疗效方面的差异;通过对2组患者之间治疗前后的神经功能缺损评分、Barthel指数的比较,分析评价它们之间远期疗效的优劣。结果:近期指标:中西医结合治疗组的MDA、CRP、HCY比西医治疗组有明显下降(P<0.05),SOD升高(P<0.05),优于西医治疗组。远期指标:中西医结合治疗组的神经功能缺损评分减低、Barthel指数提高比西医治疗组差异有统计学意义(P<0.05)。结论:中西医结合治疗急性出血性脑卒中比单纯西医治疗有明显的优势。

    Abstract:

    To reflect the unique clinical advantages of Chinese medicine in treating acute cerebral hemorrhage and stroke, and to verify scientific, practical, repeatable and operability treatment programs in our department TCM.Methods:According to the random number table,120 cases of patients with acute cerebral hemorrhage in our department were randomly divided into Western medicine treatment group (n=60) and Chinese medicine combine with Western medicine therapy group (n=60). Before and after treatment, blood superoxide dismutase, lipid peroxides in serum MDA, C-reactive protein, homocysteine indicators were observed. The difference between the short-term effect in terms of analysis and comparison of the two groups of patients were conducted; through the merits of the neurological deficit scores between the two groups of patients before and after treatment were observed, comparing the index, analysis and evaluation of long-term efficacy between them.Results:Recent indicators: Chinese medicine combine with Western medicine treatment group MDA, CRP, HCY decreased significantly (P<0.05) than those in western medicine group, and SOD increased (P<0.05), better than that of western medicine group. Long-term indicators: Chinese medicine combine with Western medicine neurological impairment score was lower intreatment group, Barthel index increased significantly differently than Western medicine treatment group (P<0.05).Conclusion:Chinese medicine combine with Western medicine treatment of acute hemorrhagic stroke has a distinct advantage over applying Western medicine alone.

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宋大桥,曹校校,俞小芬,楼建成,丁弘,潘海燕,韩彦文.中西医结合治疗急性脑出血的临床研究——中医中风病诊疗规范研究之二[J].世界中医药,2015,10(09).

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  • 收稿日期:2014-10-28
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  • 在线发布日期: 2015-09-28
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