To win the approval and acceptance of the public in developed countries such as U.S. Is critical to the internationalization of Traditional Chinese Medicine(TCM). Both acupuncture and Chinese materia medica(CMM)are crucial components to the theoretical system of TCM in our country， however， they have confronted great challenges in the world， especially Chinese materia medica in American market. Through a comparative study， this paper tries to observe the differentiation between the achievements of acupuncture and CMM in their internationalized process and analyse its reasons and implication， and thus to provide valuable suggestion to CMM for its access to American market.