To observe the curative effect of Chinese medicine bath combined with acupuncture and massage in treating shoulder-hand syndrome (SHS) after cerebral infarction(CI). Methods: A total of 80 patients with SHS in this hospital from August 2011 to May 2014 were selected and randomized into two groups, with 40 cases in the observation group and the control group respectively. The observation group was treated by Chinese medicine bath combined with acupuncture and massage on top of conventional treatment, while the control group were only treated with conventional therapy. Both groups were treated for one month. The scores of upper limb motor function (FMA), shoulder range of motion and pain numeric rating scale (NRS) in the two groups before and after treatment were recorded and compared, besides, the total effective were evaluated after treatment. Results: The differences of FMA, shoulder range of motion and shoulder pain NRS before treatment in the two groups was not statistically different(P>0.05). After treatment, FMA, shoulder range of motion and NRS score were(1.36±0.92), (2.49±0.45), and (41.89±6.67) in the observation group, while (33.58±4.53), (1.67±0.37), (3.16±1.13)in the control group, and the difference was statistically significant (P<0.05). Besides, the total effective in observation group was 92.5% (37/40), and 72.5% (29/40) in the control group, the difference was statistically significant (P<0.05). Conclusion: Chinese medicine bath combined with acupuncture and massage has a significant curative effect on SHS after CI, and it is recommended in treating SHS clinically.