To observe the effect of Jintiange capsule in relieving muscle and joint discomfort induced by Aromatase Inhibitor(AI) in patients with breast cancer. Methods: To select 50 cases of patients with breast cancer, who had developed discomfort in muscle or joint after taking AI. In a successive of twelve weeks, Jintiange capsules were given to them tree times a day, 1.2g for each time. The statistics of BPI, VAS, FACT-B, Serum E2 and FSH were taken before, during and after the capsules taken, and were then compared and analyzed by the conductors. Results: Jin Tiange capsule can effectively alleviate the patients’ average pain, pain interference, worst pain and joint stiffness. In addition, it has no obvious improvement except for pain in FACT-B. At the same time, there is no change in patients’ Serum E2 and FSH level. Conclusion: Jintiange capsule can effectively alleviate muscle and joint pain due to AI.