To observe the effects of heartfailure mixture in the treatment of chronic heart failure. Methods: Patients cardiac function and life quality were compared after the treatment of western conventional therapy combined with heartfailure mixture. Results: This study collected a total of 44 cases of chronic heart failure patients and randomly divided 22 cases into treatment group and control group respectively. After 30 days, the clinical efficacy of the total efficiency, the total efficiency of cardiac function of the treatment group were respectively 77.3%, 63.6%, better than the 50.0%，35.0% of the control group, with statistical significance(P<0.05); exercise tolerance and life quality of the treatment group were better than those of the control group, with statistical significance(P<0.05). Conclusion: Heartfailure mixture can improve the clinical symptoms and cardiac function of chronic heart failure patients, as well as the working tolerance and life quality of patients.