The thought of consolidate constitution to eliminate pathogenic factors originates from the classical wisdom that eliminate disease and prolong life in traditional Chinese medicine. The paper summarizes Professor Lin Hongshengs academic thoughts of applying consolidate constitution to eliminate pathogenic factors to treat tumor. Professor Lin thought its important to focus on the body environment as well as the tumor itself in tumor treatment. So she creatively introduced the thought of consolidate constitution to eliminate pathogenic factors to the tumor treatment and came up with the following thoughts: 1) Consolidating constitution should throughout the course of tumor treatment, and combined with methods of detoxification, bloodactivating, and stasisremoving to treat both symptoms and root causes, which enable the tumor to be controlled and embodies the thought of consolidate constitution and eliminate pathogenic factors. 2) Properly handle the relationship between tonification and purgation is the key to treat tumor. 3) The mechanism of use the principle that consolidate constitution to eliminate pathogenic factors to prevent and treat tumor includes improving the immune function, inhabiting the tumor stem cells, regulating tumor growth environment and use multiple targets for overall regulation. These academic thoughts are effective for tumor in clinical practice and also enrich the tumor theory of traditional Chinese medicine.