To research the antitumor, antiinflammatory function of Xiaoying Sanjie capsule, thereby further investigating the mechanism of Xiaoying Sanjie capsule in the treatment of thyroid adenoma．Methods:To develop S180 mouse sarcoma model and ear edema model. After giving Xiaoying Sanjie capsule and control drugs (Xiaoyao pill), test the weight, antitumor and ear edema rate of the models. Results:Xiaoying Sanjie capsule has inhibition on tumor and edema at different doses. It is more effective at higher dose, and this is significant when compared with the control group (P<0.05). Compared with the control group, Xiaoying Sanjie capsule high dose group can significantly inhibited the mice ear edema induced by xylene(P<0.05). Conclusion:The mechanism of Xiaoying Sanjie capsule in the treatment of thyroid adenoma may relate to its antitumor and antiinflammatory effects.