To observe the effect of Bailing Capsule on function of liver and kidney of rat after allograft liver transplantation and to explore the protective mechanism of Bailing capsule of liver, renal ischemia / reperfusion injury in liver transplantation. Methods: We randomly divided ten rats into blank control group, 40 model group and Bailing capsule group, and perform allograft liver transplantation cross on two groups of rats by two cuff method. After taking Baling capsule for 14 days, the aspartate aminotransferase(AST), alanine aminotransferase(ALT), total bilirubin(TBIL), cystatin C in renal function(Cys C), blood urea nitrogen(BUN), serum creatinine(Cr), serum malondialdehyde(MDA), lactate dehydrogenase(LDH)and serum superoxide dismutase(SOD)level were detected to evaluate the effect of Bailing capsule on function of liver and kidney of the rats. Results: The AST, ALT, TBIL, LDH, Cys C, BUN and Cr of Bailing capsule group decreased, serum SOD elevated significantly compared with the model group and the situation before treatment. P<0.05, the difference was significant. Conclusion: Bailing capsule can promote the function of SOD in removing the free radical operation after liver transplantation, restrain the inhibiting lipid peroxidation, reduce the damage of rejection reaction and hepatic and renal ischemia/reperfusion, improve the recovery of liver and kidney, which all shows that it has protective effect during the process of liver transplantation.