Abstract:To explore the correlation between ankle brachial ratio and laser Doppler blood flow perfusion among different syndrome types of diabetes ulcer patients. Methods: To divide diabetes ulcer into qi deficiency and blood stasis type and dampness and hot accumulation type based on clinical TCM(traditional Chinese medicine) differentiation, and set up a normal control group. To detect the erythrocyte sedimentation rate, cholesterol, blood lipid, low density lipoprotein(LDL)-cholesterol, high-density lipoprotein(HDL)-cholesterol, ankle brachial volume ratio, laser Doppler perfusion changes in different groups. Results: Diabetic ulcers ankle brachial ratio is significantly lower than that of the normal control group, besides, the ratio of dampness and hot accumulation group is lower than that of the qi deficiency and blood stasis group(P<0.01). Compared to normal control group, laser Doppler perfusion percentage significantly decreased. In addition, qi deficiency and blood stasis group decreased greater than that of the damp and hot accumulation group(P<0.01). Logistic regression analysis shows that TCM syndrome types of diabetes ulcer have close correlation with ankle brachial ratio and laser Doppler blood flow perfusion. Conclusion: There exists certain correlation between ankle brachial ration and laser Doppler perfusion. The differences among groups illustrate diabetes ulcer patients suffer from varying extent of blood deficiency, and this is more obvious in qi deficiency and blood stasis type patients. Also, TCM syndrome types of diabetes ulcer have strong relevance with ankle brachial ratio and the duration of diabetes.