To explore the mechanism of Xing Shen Qi Bi Needling therapy in treating acute cerebral infarction by comparing the degree of nervous functional defect, limbs movement function and daily activities.Methods:Patients meeting the inclusion criteria of 60 cases were randomly divided into group A and group B, 30 cases in each group. Group A adopted Xing Shen Qi Bi Needling therapy with basic treatment and group B received routine acupuncture plus basic treatment. Treatment lasted for ten days. Both groups were evaluated by Clinical Nerve Functional Impairment Level Score Standard (CSS), Fugl-Meyer (FMA) and modified Barthel index(MBI) before and after the treatment.Results:Firstly, the CSS score after treatment obviously decreased (P<0.01), there was a more obvious effect in group A than group B (P<0.05). Secondly, the FMA score increased obviously after treatment (P<0.01), the result of group A was better than group B (P<0.05). Thirdly, the MBI score after treatment increased obviously (P<0.01), the effect of group A was better than group B (P<0.05).Conclusion:Xing Shen Qi Bi Needling therapy has significant efficacy on patients with acute brain infarction in reducing neurological functional deficit, limbs movement function and daily activities, the efficacy is superior than routine acupuncture.