To investigate the clinical efficacy of Fufang Danshen injection combined with magnesium sulfate on patients with pregnancy induced hypertension syndrome. Methods: Ninety patients in our hospital were randomly divided into a observation group and a control group, with 45 patients in each. The control group was given conventional western medical treatment. The observation group was given a plus Fufang Danshen Injection. The treatment course was two weeks. Record the changes in blood ET(endothelin) and NO(nitric oxide) of the two groups, besides, the mother and child situation were observed after treatment. Results: After treatment, the decrease level of ET in the observation group is greater than that of the control group, and the increase level of NO is also greater in the observation group, and the differences are statistically significant(P<0.05). Maternal and neonatal outcomes comparison shows that in fetal heart rate abnormalities, caesarean section, neonatal asphyxia, stillbirth aspects, the observation has lower level than the control group, with P<0.05. Conclusion: Fufang Danshen injection combined with magnesium sulfate has high efficacy in treating pregnancy induced hypertension syndromes. The possible mechanism might be balancing ET and NO to regulate blood pressure, thereby reducing abnormal fetal heart rate, incidence of stillbirth, neonatal asphyxia, and caesarean section. It is worthy of clinical promotion.