To observe Children Huadu powder’s clinical curative effect for the treatment of pediatric dental ulcer.Methods:Total 78 patients with infantile oral ulcer during May, 2013 to December, 2015 were chosen and given Children Huadu powder topical treatment. And another 78 cases were set as the control group, receiving local lint spraying mouth spray treatment. In addition, both of the two groups were given oral compound vitamin and symptomatic treatment.Results:The total effective rate of the treatment group was 100%, while control group 75.7%. And cure time and analgesic time of the treatment group is shorter.Conclusion:Children Huadu powder has advantages of short cure time with better analgesic effect.