To evaluate Bo-Ai capsule’s hemodynamic effects on anesthesia dogs. Methods:The experiment adopted the cardiac catheterization intervention to observe the Bo-Ai capsule’s hemodynamic effects on anesthetic dogs. The dosage of the capsule was set at 2.24 g/kg/d, 1.12 g/kg/d, 0.56 g/kg/d, and the captopril, by duodenal administration, was set as the positive control drug. Changes of blood dynamics of anesthetic dogs was observed. Results:Compared with model group, systolic blood pressure and total peripheral vascular resistance decreased significantly in large and middle dose groups of Bo-Ai capsule after 1 to 2.5 hours (P<0.05, P<0.01). Compared with model group, diastolic blood pressure decreased significantly in large Bo-Ai capsule dose groups after 1.5 hours (P<0.05). Conclusion:It is obvious that Bo-Ai capsule has antihypertensive effect on systolic blood pressure, total peripheral vascular resistance and diastolic blood pressure, which provides references for the antihypertensive mechanism of Bo-Ai capsule.