Analysis of the types and characteristics of adverse reactions caused by traditional Chinese medicine preparations, to explore the management countermeasures of traditional Chinese medicine preparations. Methods:One hundred and eighty adverse reactions reports of traditional Chinese medicine preparation of patients who received treatment from January 2013 to December 2015 in the hospital were randomly selected. Related factors of the adverse reactions to Chinese medicine preparation were retrospectively analyzed, including gender, age, medicine form, administration and the involved the organs or systems) and management measures were suggested according to corresponding adverse reactions factors. Results:The incidence of adverse reactions occurred in female patients was higher than that in male with no statistically significant difference (P>0.05). Patients of 11 to 20 years old (27.2%) and above the age of 61 (28.3%) may much easier been attacked compared with patients in other age group with statistically significant differences (P<0.05); adverse reactions mainly occured within 1 hours after medicine administration (78.9%), and the difference was statistically significant (P<0.05). Intravenous injection (53.9%) and oral preparation of traditional Chinese medicine (17.8%) are the most common formulations caused adverse reactions of Chinese medicine, compared with other forms of Chinese medicine, with statistically significant difference (P<0.05). The incidence of adverse reactions of intravenous administration (66.1%) was significantly higher than that of oral preparations, topical preparations and other ways of administration, which showed statistically significant difference (P<0.05). The main Chinese medicine adverse reactions involved organs or systems are the skin (38.3%) and digestive system (26.1%) and their incidences of adverse reactions was significantly higher than that of the circulatory system, respiratory system, circulatory system, etc., statistically significant difference (P<0.05). Conclusion:there is still a lack of in-depth research and comprehensive understanding on adverse reaction of traditional Chinese medicine and medication safety in clinic. More attention should be paid to the monitoring of adverse reactions and rational use of traditional Chinese medicine preparation to improve the medication safety of clinical Chinese medicine preparation.