To observe the curative effect of Huangqi injection on stage III gastric cancer and its effects on the body’s immune function.Methods:A total of 60 patients in stage III gastric carcinoma admitted in our hospital during January 2009 to January 2014 were randomly divided into the control group and the observation group.Also,30 cases of healthy people were recruited as healthy control group.Both of the two groups had received radical operation and took the conventional EOF scheme chemotherapy after surgery.The observation group was given Huangqi injection 30 mL with 250 mL 0.9% sodium chloride solution by intravenous drip on the basis of conventional treatment,1 time/ day,20 days.After treatment,compared the two groups in the aspects of quality of life (Karnofsky score),peripheral blood mononuclear cells,and the accumulative survival rate.Detected the peripheral blood Th1,Th2,and the cell percentage change of the three groups.Results:1) Huangqi injection could obviously increase the quality of life in the patients in stage III gastric cancer,and simultaneously increase the accumulative survival rate of the patients.2) Th1/Th2 ratio in the patients with gastric cancer was significantly lower than that of the healthy control group.However,Th1/Th2 ratio of the two groups both decreased after treatment,and the descending trend in the observation group was more obvious (P<0.05).Conclusion:For patients in stage III gastric carcinoma,CD4+T cells are abnormal and Huangqi injection can improve the quality of the patients’ life by regulating the levels of CD4+T cells.