To explore the effect of different producing area and same dose of Aconite Root contained Poge Heart-saving Decoction combined with conventional western medicine in the treatment of heart failure and its effect on heart function.Methods:A total of 80 cases of refractory heart failure patients in our hospital during March 2015 to October 2015 were divided into experimental group and control group by envelope extraction method,40 cases in each group.The control group was treated with routine western medicine while the experimental group took different producing areas (Yunnan and Henan) but same dose of Aconite Root contained Poge Heart-saving Decoction combined with routine western medicine treatment.The therapeutic effect of two groups was compared at the end of the treatment.Results:Heart function classification of the experimental group was better than that of the control group (P<0.05); Chinese medicine syndrome score of the experimental group was (17.04 ±5.23),the control treatment group was (35.67±5.98); left ventricular shoot ejection fraction and cardiac output of the experimental group were higher than those of the control group (P<0.05); Aconite Root produced in Yunnan and Henan both had good effect and their clinical efficacy had no significant difference (P>0.05),but Yunnan Aconite Root showed more adverse reaction than Henan Aconite Root (P<0.05).Conclusion:Different areas of the same dose of Aconite Roots contained Poge Heart-saving Decoction combined with routine western medicine has good clinical effect on refractory heart failure.