To observe the clinical efficacy of Wind-damp-dispelling and pain-relieving Capsule with Sodium Hyaluronate in the treatment of knee osteoarthritis.Methods:In out-patient of our hospital,120 cases diagnosed with knee osteoarthritis were randomly divided into 2 groups.Treatment Group was treated with Wind-damp-dispelling and pain-relieving Capsule and a weekly injection of 2 ml Sodium Hyaluronate into knee joint cavity and the Control Group was treated with a weekly injection of 2 ml Sodium Hyaluronate into knee joint cavity.The treatment course was 5 weeks.The total effective rate,visual analogue scales (VAS),Western Ontario and McMaster University Osteoarthritis Index (WOMAC) were compared in 2 groups after treatment.Results:In Treatment Group,the total effective rate was 93.3%,and 83.3% in Control Group,the 2 groups showed significant difference (P<0.05).WOMAC and VAS scores of two groups of patients declined significantly after the treatment (P<0.05),WOMAC and VAS scores of two groups declined significantly after the treatment (P<0.01) and the Treatment Group had significantly better results than the Control Group (P<0.05).Conclusion:Wind-damp-dispelling and pain-relieving Capsule with Sodium Hyaluronate has higher clinical practical value in treatment of knee osteoarthritis and worthy to be promoted in clinical application.