To study the effect of modified Fumai Decoction on the quality of life of patients with arrhythmia.Methods:A hundred and six patients with arrhythmia who received treatment in our hospital from January 2014 to June 2015 were included as the study subjects and were randomly divided into the observation group and the control group, with 53 cases in each. Patients in the control group were treated with propafenone, while those in the observation group were given modified Fumai Decoction. Patients received 4-week treatment and the curative effects, symptom scores and the quality of life were compared between the two groups before and after treatment.Results:The total effective rate of the observation group was 98.11%, which was significantly higher than that of the control group (84.91%), showed there was statistically significant difference (P<0.05). The symptom scores of the two groups were significantly lower than those before treatment, and scores of the observation group were significantly lower than those of the control group with statistically significant difference (P<0.05). After treatment, the physiological function and social function of the observation group were significantly higher than those before treatment, while physiological function of the control group had significantly higher compared with that before treatment, which showed statistically significant difference (P<0.05). The physiological function of the observation group was significantly higher than that of the control group, showing the difference was statistically significant (P<0.05).Conclusion:Modified Fumai Decoction in the treatment of arrhythmia obtain better curative effect and is beneficial to improve the patient’s quality of life, worthy of spread and application.