To evaluate the effect of Buyang Huanwu decoction on coagulation and blood rheology indexes in aged patients who received hip replacement for intertrochanteric fracture.Methods:Seventy cases of aged patients with intertrochanteric fracture who received hip replacement were randomly selected and divided into two groups.The experimental group (n=35) received traditional Buyang Huanwu decoction and the control group (n=35) received low molecular heparin therapy.To observe the coagulation indexes and hemorheology indexes of tje two groups of subjects before and after treatment,including Prothrombin time (PT),activated partial thromboplastin time (APTT),D-dimer(D-D) and other blood rheology indexes:high shear rate of whole blood viscosity,middle shear rate of whole blood viscosity,low shear rate of whole blood viscosity and plasma viscosity.Results:The blood coagulation indexes and hemorheology indexes before treatment between the two groups had no statistical significance (P>0.05).After treatment,the two groups of patients’ blood coagulation indexes and hemorheology indexes were all significantly improved,while the improvement of the experimental group was significantly better than the control group (P<0.05).The results of leg color doppler ultrasound examination showed that the incidence of venous thrombosis (DVT) in the experimental group is less than that in the control group,and the difference between the two groups has statistical significance(P<0.05).Conclusion:Buyang Huanwu decoction can improve hypercoagulable state of aged patients who suffered intertrochanteric fracture and received hip replacement,activate fibrinolytic system,regulate blood viscosity and reduce the incidence of venous thrombosis (DVT).