Inherit the academic thought of Yanzhao Gao Shi on acupuncture，and to observe the clinical effect of Tiaodu-anshen acupuncture combined with Guipi decoction on the treatment of insomnia with heart-spleen deficiency type.Methods:Seventy-six insomnia patients with heart-spleen deficiency type were randomly divided into two groups，38 cases in treatment group，36 cases in control group（2 cases fell off).On the basis of oral Guipi decoction，patients in treatment group were treated by Tiaodu-anshen acupuncture while patients in control group were treated by common acupuncture.The treatment course was four weeks.The sleep quality was evaluated by Pittsburgh sleep quality index（PSQI)，the curative effect was evaluated by the score-reducing rate of PSQI.Results:There was no significant difference on curative effect between two groups（P>0.05),but the score-reducing rate of PSQI in treatment group was superior to that in control group（P<0.05).The improvements of sleep quality，fall asleep time and sleep disorders after treatment in treatment group was superior to those in control group（P<0.05).Conclusion:Combined therapy of Tiaodu-anshen acupuncture and Guipi decoction on the treatment of insomnia with heart-spleen deficiency type has exact effect，and different acupuncture prescription and acupuncture sequence were the influence factors on curative effect.