To observe the effect of Xihuang pills combined with concurrent chemoradiotherapy on locally advanced cervical cancer.Methods:Sixty-two patients with locally advanced cervical cancer were randomly divided into two groups: patients in control group were treated with concurrent chemoradiotherapy, and patients in observation group were treated with Xihuang pills combined with concurrent chemoradiotherapy. Indexes as the objective response rate (RR), toxicities, quality of life (QOL), and cellular immune status were compared.Results:There was no significant difference in RR between the two groups (P>0.05). Observation group was superior to control group in the aspects of TTP, toxicity, QOL and anti-tumor immune(P<0.05).Conclusion:Xihuang pills combined with concurrent chemoradiotherapy has advantages in improving QOL, reducing side effects, and activating anti-tumor immune response in patients with locally advanced cervical cancer.