To observe the effect of Yiqi Huayu decoction combined with functional exercise in treating postoperative residual pain after lumbar degenerative disease. Methods: A total of 134 patients with postoperative residual pain after lumbar degenerative disease admitted in our hospital from December 2012 to December 2014 were selected, then divided into two groups by random digital table method. Sixty-seven patients treated with functional exercise as control group, and the other 67 patients treated with Yiqi Huayu decoction combined with functional exercise as observation group. VAS score, ODI score, JOA score, SF-36 score, ADL score were recorded before and after treatment. Results: With the extension of time, VAS score ,ODI score decreased in two groups (P<0.05), while JOA score, SF-36 score, ADL score increased in two groups (P<0.05). After treated for 1 week, 2 weeks, 3 weeks, VAS score ,ODI score in observation group were lower than those of the control group (P<0.05), while JOA score, SF-36 score, ADL score in observation group were higher than those of the control group (P<0.05). Conclusion: Yiqi Huayu decoction combined with functional exercise has significant effect on relieving postoperative residual pain after lumbar degenerative disease. Besides, it can improve lumbar function and patient′s quality of life.