To observe the effect of Supplemented Angelica Blood-Tonifying Decoction on quality of life of patients with chronic heart failure combined with Anemia.Methods: Total 72 cases of chronic heart failure combined with anemia were randomized into treatment group (36 cases) and control group(36 cases). Treatment group was given Supplemented Angelica Blood-Tonifying Decoction on the basis of western medicine, control group was given western routine medicine, both groups were treated for 4 weeks. Before and after treatment, Chinese medicine symptom score, hemoglobin, LVEF, MLHFQ score were observed. Results: The total effective rate of symptom score of the treatment group and control group was 80.56% and 55.56% respectively, with significant difference between the two groups (P<0.05).The levels of Hb in both groups were improved after treatment, especially in the treatment group(P<0.05), the scores of MLHFQ in both groups decreased after treatment, especially in the treatment group(P<0.05).Conclusion: Supplemented Angelica Blood-Tonifying Decoction could correct anemia in chronic heart failure patients, as well as improve heart function and quality of life.