To observe the effect of Liuwei Dihuang decoction combined with insulin in treating gestational diabetes,and their impact on blood sugar,mode of delivery,maternal outcome.Methods:A total of 120 cases of pregnant patients diagnosed of gestational diabetes with liver and kidney deficiency syndrome and admitted into obstetrics and gynecology hospital in January 2014-June 2015 were randomly divided into 2 groups with 60 cases in each.The control group received diet therapy combined with insulin therapy,and the dosage of insulin was adjusted based on blood glucose control.On the basis of the control group,the observation group also received Liuwei Dihuang decoction,2 times/day,7 days/a session of treatment.Both groups received the treatment until childbirth.The clinical efficacy of the two groups were observed.Results:After treatment,the observation group has higher efficiency,and the difference was statistically significant (P<0.05).Compared before treatment,both the observation group and the control group improved in fasting blood glucose,postprandial 2 h blood sugar control and the differences were statistically significant (P<0.05),besides,the improvement of the observation group is better than the control group,and the differences were statistically significant (P<0.05).In the control group,the incidence of hypertensive disorders in pregnancy and cesarean section yields higher than those of the observation group,and the difference was statistically significant(P<0.05).Also,in control group,the incidence of preterm newborn infant,huge infant,fetal distress and neonatal asphyxia were higher than those of the control group and the differences were statistically significant (P<0.05).Conclusion:Liuwei Dihuang decoction combined with insulin can effectively control blood sugar and treat kidney deficiency syndrome of gestational diabetes in pregnant women.Also,it can reduce the incidence of gestational hypertension and cesarean section rate,at the same time,reduce the incidence of preterm infant,huge infant,fetal distress and neonatal asphyxia,which is worthy of clinical application.