To investigate syndrome distribution characteristics of Helicobacter pylori (Hp) related chronic non-atrophic gastritis and establish theoretical basis for TCM syndrome differentiation.Methods:To select 408 cases of chronic non-atrophic gastritis patients including Hp positive patients 161 and Hp negative patients 247. Analyze their syndrome scores by TCM syndrome factor differentiation and compare the common lesion location of the two groups as to study the syndrome distribution characteristic of Hp related chronic non-atrophic gastritis.Results:1）The symptom characteristics of Hp positive group shows that the lesion site are mainly the stomach, spleen, and liver, and the basic symptoms are mainly qi stagnation, heat, dampness, yin deficiency, phlegm, yang deficiency, qi deficiency related. However, the lesion sites of the Hp negative group are mainly the stomach, spleen, and liver and the basic symptoms are heat, qi stagnation, dampness, yin deficiency, phlegm, qi deficiency, and yang deficiency related. 2）The occurance frequencies of syndrome elements of the two groups have no significant difference(P>0.05). However, dampness syndrome in Hp negative group is higher than that of the Hp positive group(P=0.036<0.05), but other symptoms has no statistically difference(P>0.05).Conclusion:1）Stomach, spleen and liver are the primary lesion locations of chronic non-atrophic gastritis. The main symptoms are a mixture of deficiency and excess or mixture of cold and heat. Besides, Qi stagnation, dampness and heat are important pathological factors of chronic non-atrophic gastritis. 2）The syndrome distribution characteristics of Hp positive patients has no obvious difference with Hp negative group, and the syndrome distribution has no obvious correlation with Hp infection.