To investigate the effect of acute cerebral infarction by TCM clinical treatment pathway.Methods:Total 70 cases of acute cerebral infarction between May 2015 to May 2016 in our hospital were randomly divided into clinical pathway group and conventional therapy group with 35 cases in each group.The conventional therapy group adopted the general symptomatic and supportive treatment,and the clinical pathway group adopted the TCM clinical path mode treatment,and followed-up lasted for 3 months.Results:Total effective rate of the clinical pathway group (91.43%)was much higher than conventional clinical therapy group (71.43%),NHSS score,duration of hospital stay and treatment costs of the clinical pathway group were much lower than the conventional treatment group,the readmission rate within 3 months of the clinical pathway group (11.43%) was significantly lower than the conventional treatment group (31.43%) (P<0.05).Conclusion:Clinical medicine pathway treatment is effective in acute cerebral infarction patients in improving clinical efficacy and nerve function,shortening time of hospitalization,reducing treatment costs and readmission rates,which is worthy of clinical application.