To observe the clinical effect of Chinese medicine iontophoresis in the treatment of spastic hemiplegia after stroke. Methods:From June 2014 to May 2015, 60 patients with spastic cerebral palsy were randomly divided into treatment group and control group. Two groups were given fundamental treatment, and treatment group was additionally treated with Chinese medicine iontophoresis. Twenty-eight days after the treatment, degree of limb spasm, motor function, daily living ability and clinical neurological function impairment were evaluated. Results:Ashworth classifications for limb spasm degree were compared in the treatment group before and after the treatment (Hc=23.359, P<0.01) and the comparison was made between the two groups after treatment (Hc=21.432, P<0.01), whose differences were both statistically significant. Fugl-Meyer score, BI index of the treatment group after treatment increased and NIM decreased, compared with before treatment, which all showed statistically significant differences (P<0.05). Fugl-Meyer rating, BI and NIM index of the control group after treatment were compared with those before treatment, which also showed significant difference (P<0.05). After treatment, Fugl-Meyer score and BI index increased more remarkably in the treatment group and the decline of NIM was more apparent than that of the control group, with statistical difference (P<0.05). Conclusion:Chinese medicine iontophoresis may relieve the spasm degree of spastic paralysis caused by cerebral apoplexy, enhance patients′ movement, reduce neurological impairment, and improve patients′ quality of life.