By comparing the function of Tusizi (Cuscutae semen) in ancient herbal literature,ancient prescriptions and modern national pharmacopoeia,it can be assured that basic functions of Tusizi were collected in Chinese Pharmacopoeia.However,the functions include strengthening muscle and bone,stimulating saliva and reducing thirst,calming mind,and hemostasis as well as its application in wasting-thirst syndrome,bi-syndrome,stroke,ulcer,pain,dysuria and urodynia were not collected in Chinese Pharmacopoeia.Combined with pharmacodynamic study and clinical usage,Tusizi′s potential functions in strengthening muscle and bone,stimulating saliva and reducing thirst,dispelling wind and cold,removing dampness,suppressing hyperactive liver and calming endogenous wind are confirmed.