To summarize the syndrome elements of hepatitis B-caused cirrhosis (HBC), to analyze its composition and distribution and to explore the characteristics of its pathogenesis in HBC patients. Methods:The four-diagnostic information of 294 HBC cases was collected. The summary of syndrome elements and the symptoms contribution degree were carried out by an entropy-based complex systematic classification method and the composition and distribution rules were analyzed according to the diagnostic threshold value. Results:There were7 syndrome elements in HBC, namely spleen deficiency, kidney qi deficiency, liver yin deficiency, dampness-phlegm, qi stagnation, liver depression and dampness-heat. Moreover, at least one or more syndrome elements can be concluded from one patient. Spleen deficiency, qi stagnation and dampness-heat were those with highest frequency. Conclusion:The entropy-based complex system method may be used to summarize syndrome elements for HBC. The pathogenesis of HBC is complicated and its main factors may be related to spleen deficiency, qi stagnation and dampness-heat.