Abstract:Most of CM internal diseases were illustrated by type according to 5 zang organs system in Chinese Internal Medicine, while meridians and collaterals of limbs and qi, blood and body fluids diseases were introduced by separated chapters according to the etiology and pathogenesis. The prescriptions in it were mostly ancient ones, and attributive channels of most medicine in the prescriptions belonged to the five internal organs. Combining disease orientation in organs with the attributive channels of medicine, once the orientation was targeted clinically, then the medicine should be chosen from those belonged to corresponding channels, in order to enhance the targeting of clinical medicine. Qi, blood and body fluids diseases were rooted in dysfunctional organs so they should also be attributed by this category, more beneficial to medication.