To research the distribution of patients with stroke in six Qi and effect on syndromes of yin and yang in two fire years of 2008 and 2013，so as to provide a new method to prevent and treat stroke.Methods:The cases with stroke in hospital in 2008 and 2013 were divided into 6 groups according to the variation of six Qi，which were the first Qi，the second Qi，the third Qi，the forth Qi，the fifth Qi and the end Qi.The occurrence rate of stroke，the rate of different types of stroke and syndrome of yin and yang in these two fire years.Results:There were more patients of stroke and CI(cerebral infarction)in the third Qi and the fourth Qi than the other four Qi in 2008 and 2013.It has statistically significant difference compare with the other four Qi（P<0.05，P<0.01）.CH(cerebral hemorrhage)in the second Qi were more than the other four Qi in 2008 and 2013.But there was no obvious difference between 2008 or 2013 and other four Qi（P>0.05）.The rate of yang syndrome in 2008 was higher than that of yin in 2013,while the rate of yin syndrome in 2013 was higher than that of yang in 2008.There were differences in district distribution between these years(P<0.0001）.Conclusion:The distribution of patients with stroke in the second Qi and the third Qi is more than other four Qi in Fire years of 2008 and 2013.The rate of yang syndrome in ample Fire years is more than that of yang in inadequate In Fire years，while the rate of yin syndrome in inadequate Fire years is more than that of yin in ample Fire years.The results should be promoted to prevent and treat stroke.