To Observe of Juanbi square with the treatment of rheumatoid arthritis (Rheumatoid Arthritis, RA) influence the efficacy and quality of life of patients.Methods:A total of 86 cases of RA patients were selected from October 2013 to June 2015 in Tangshan workers' hospital, were randomly divided into control group and observation group, 43 cases in each group, the control group was treated with methotrexate and meloxicam, observation group with Juanbi recipe joint and acupoint, 30 d for 1 courses.The clinical indexes and lab indexes were compared.The curative effect was evaluated by ACR20,ACR50,ACR70 which was made by the United States Institute of Rheumatology.SF-36 scale was used to evaluate the quality of life.The adverse reactions were recorded.Results:Compared with control group, after treatment,the morning stiffness time,the number of joint tenderness,the walking time for 20 miles, VAS score of pain,VAS score of doctor,VAS score of patients, HAQ score and the level of CRP decreased greatly;the bodily pain, general health and vitality improved greatly(P<005);the ACR20,ACR50 and ACR70 was 814%,651% and 359%,respectively;all were higher than that in control group of 605%,395% and 140%(P<005),The incidence of adverse reaction rate was similar between the two groups(P>005).Conclusion:External Juanbi recipe is effective and safe for RA,and is worthy of widely clinical use.