To investigate the effects of Huoxue Huayu Decoction Combined with western medicine in the treatment of acute ischemic cerebral apoplexy patients curative effect observation and influence on blood rheology in patients.Methods:From the October 2014 ～ October 2015 year in our hospital in patients with acute ischemic stroke in 102 cases，were randomly divided into treatment group 51 cases and control group 51 cases.The control group using conventional western medicine treatment，the treatment group in the control group on the basis of blood stasis treatment.Two groups were treated for 2 weeks.The treatment effect was compared between the two groups，before and after treatment，NISS score，BI score，blood rheology index level and the adverse reactions during the treatment.Results:The total effective rate of the treatment group(8824%)was higher than the control group(7059%)(P<005); The NIHSS scores of the two groups decreased significantly after treatment(P<005); The NIHSS score of treatment group was lower than the control group after treatment(P<005); The BI scores of the two groups increased significantly after treatment(P<005); The BI score of treatment group was higher than that of the control group after treatment(P<005); In the treatment group，blood rheology levels in treatment decreased significantly(P<005); Treatment group，blood rheology levels in treatment were lower than those in the control group(P<005); The two groups had no serious adverse reaction of drugs.Conclusion:Huoxue Huayu Decoction combined with western medicine therapy in patients with acute ischemic stroke，and can obviously improve the blood rheology，safe and reliable，worthy of study.