To study the clinical efficacy of treating nerve-root type cervical spondylosis patients with acupuncture and thunder-fire moxibustion as well as Chinese medicine. Methods:A total of 136 cases were randomly divided into control group of 68 cases and treatment group of 68 cases. Patients in the control group were treated with acupuncture and Pubescent Angelica and Taxillus Impediment-Alleviating Decoction; while patients in the treatment group were treated with thunder-fire moxibustion on the basis of control therapy, 10 days for a course, 2 courses for treatment. Aimed at comparing the effect, the neck and shoulder pain with VAS, PPI and PRI scores and the nerve function with JOA scores, change of blood rheology indexes and change of ESR and CRP levels were evaluated. Results:The clinical effect of treatment group was significantly better compared with control group, and its clinical effective rate was 912%,which was higher than the control group’s 75% (χ2=6332，P<005）;The neck shoulder pain and neurological function of patients in the treatment group were better improved than the control group, and the VAS,PPI and PRI scores were respectively(215±084), (211±029) and (1242±137), which were lower than the control group’s (430±113), (256±042) and (2036±154), while the JOA score was (1583±278), which was significantly higher than that of the control group（1127±260）(P<005）; The improvement of hemodynamic of patients in the treatment group was better than the control group, and the blood rheology indexes were lower than the control group (P<005）;The levels of ESR and CRP were lower than the control group (P<005). Conclusion:Clinical efficacy of treating nerve-root type cervical spondylosis patients with acupuncture and thunder-fire moxibustion as well as Chinese medicine has satisfactory clinical effect. The therapy can effectively alleviate the neck and shoulder pain and improve the neurological function, which shows the advantages and characteristics of treating cervical spondylosis with Chinese medicine. The mechanism may be associated with improving the local blood rheological state of cervical vertebrae, which is worth of wide application in the clinical practice.