中医药对高血压前期血压影响的Meta分析
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湖北省教育厅自然科学研究计划项目(编号:B2013169);宜昌市医疗卫生科研项目(编号:A15301-33)


Effect of Chinese Herbal Medicine on Blood Pressure in Pre-hypertensive Cases:A Meta-analysis
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    目的:系统评价中医药对高血压前期血压的影响。方法:计算机检索国内外关于中医药干预高血压前期的临床随机对照试验,使用I2评估各研究之间的异质性,并用RevMan 520软件进行Meta分析。结果:共纳入8篇文献,1005例受试者。Meta分析结果提示,与对照组相比,试验组在降低收缩压(WMD:-365;95%CI:-535~-194;I2:87%)及舒张压(WMD:-258;95%CI:-430~-086;I2:93%)方面均优于对照组,2组间的差异具有统计学意义(P<001)。结论:在生活方式干预的基础上,加用中医药干预有助于进一步降低血压水平。

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    To evaluate the effect of Chinese herbal medicine on blood pressure in pre-hypertensive cases.Methods:Domestic and international databases were searched for relevant randomized controlled trials(RCTs)which investigated the effect of Chinese herbal medicine on blood pressure in pre-hypertensive cases.Heterogeneity of cross-studies was assessed,using I2All meta-analyses were conducted through RevMan 520Results:Eight RCTs involving 1005 subjects were selected.Meta-analysis demonstrated that the test group reduces the level of both systolic blood pressure(WMD:-365; 95%CI:-535~-194;P<001,I2:87%)and diastolic blood pressure(WMD:-258; 95%CI:-430~-086;P<001; I2:93%),compared with the control group.The difference was statistically significant.Conclusion:Basing on lifestyle intervention,Chinese herbal medicine helped reducing the level of blood pressure.

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刘宏军,许强,刘学会.中医药对高血压前期血压影响的Meta分析[J].世界中医药,2016,(11).

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  • 收稿日期:2015-12-30
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  • 在线发布日期: 2016-12-30
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