To investigate the clinical efficacy of transurethral plasmakinetic resection of prostate(PKRP)combined with Yishen Zhuyu Decoction in the treatment of benign prostatic hyperplasia(BPH)and its influence on sex hormone levels.Methods:A total of 116 cases of March 2014-2016 year in June the hospital treated BPH patients were randomly divided into control group(n=58)and observation group(n=58),2 groups were treated with PKRP,the control group during the perioperative period of routine treatment,the observation group in the control group and Yishen Zhuyu Decoction treatment.Statistics of 2 groups of surgical conditions and the clinical efficacy of each card type,recorded and compared the preoperative and postoperative 8 weeks clinical index and sex hormone levels in the 2 groups,statistical analysis of postoperative complications of the 2 groups.Results:the liquid content of hemoglobin,bladder washing time and catheter retention time had no significant difference between the 2 groups in flushing(P>0.05);control group,blood stasis syndrome,bladder coke under the damp heat syndrome,kidney yin deficiency,kidney yang deficiency syndrome and lung heat syndrome in patients with closed the total effective rate was 73.91%,40%,respectively 46.15%,42.86% and 40%,respectively,compared with the observation group 95.45%,83.33%,90%,100% and 100% was significantly decreased(P<0.05);compared with the preoperative,postoperative 8 weeks,2 groups of PVR,IPSS score,QOL score and E2 in the observation group,LH and FSH levels were significantly decreased,and the observation group was significantly lower than that of control group(P<0.05 or P<0.01); and the 2 group of MFR and T in the observation group,PRL levels were significantly increased,and the observation group was significantly higher than control group(P<0.01); the complication rate of observation group(10.34%)was significantly lower than control group(25.86%)(P<0.05).Conclusion:PKRP combined with Yishen Zhuyu Decoction can significantly improve the clinical symptoms of patients with BPH,regulate the level of sex hormone in patients,improve clinical efficacy and reduce the incidence of postoperative complications,the curative effect was significantly better than conventional treatment after PKRP.