To observe the clinical curative effect of combine traditional Chinese and Western medicine in treating insomnia.Methods:Selected 108 cases of insomnia patients in our hospital from January 2015 to April 2016.Adopted random number table to divide patients into treatment group and control group.54 cases each group.Treatment group adopted combined treatment of traditional Chinese medicine and Western medicine.Control group adopted simple Western drug therapy.Observe the treatment effect and adverse reaction of two groups.Results:The total effective rate of treatment group was 90.7%，control group was 74.1%.Treatment group was obviously higher than control group，the difference had statistical significance(χ2=5.173，P<0.05).Treatment group patients’weakness，thirsty，dizziness，sleepiness and illusion were all less than control group.The total adverse reaction cases of treatment group were obviously less than control group，the difference had statistical significance(χ2=5.708，P<0.05).Conclusion:The curative effect of combine traditional Chinese and Western medicine was better than simple Western drug therapy in treating insomnia.