To explore the characteristic of Chinese medicine syndromes in advanced malignant tumor patients with malnutrition. Methods:Carry on the statistical analysis of the characters distribution of traditional Chinese medicine syndromes which exist in patients screened with the NSR-2000 tools who had malnutrition risk and also complied with the deficiency syndrome diagnostic standard in traditional Chinese medicine. Results:Totally 267 investigated cases of advanced malignant tumor patients, among which 187 cases were malnutrition risk patients and 161 cases were in according with the deficiency syndrome diagnostic standard. The traditional Chinese medicine syndromes distribution characters was different in various kinds of malignant diseases. Overall,in this study, more advanced malignant tumor patients with nutrition risk manifested qi deficiency and spleen deficiency syndrome. Conclusion:This study preliminary suggested that a higher proportion of advanced malignant tumor patients with malnutrition risk came out with deficiency syndrome. The syndrome distribution of different kinds of diseases was various and qi and spleen deficiency were more common. This conclusion provided certain references for clinical diagnosis and treatment in the therapy of advanced tumor patients with malnutrition. Also this study laid a foundation for further research on the intervention of malnutrition risk in advanced malignant patient by traditional Chinese medical methods.