To observe the clinical curative effect of Traditional Chinese Medicine (TCM) external application and decoction combined with acupuncture and fumigation treatment in treating of knee joint synovitis. Methods:Eighty-four cases of knee joint synovitis were randomly divided into two groups:control group and treatment group with 42 cases in each. The control group was treated with acupuncture and fumigation treatment, the treatment group was treated with TCM external application and decoction on the basis of the control group. Taking 7 days as a course of treatment. The clinical efficacy were observed after 2 courses of treatment. Results:The total efficiency of the treatment group was 95.23%, significantly higher than that of the control group (80.95%), with statistical significance (P<0.05. Conclusion:TCM External application and decoction combined with acupuncture fumigation therapy perform better than acupuncture fumigation treatment.