Focused on medication frequency,drug combination and dosages,this paper is to summarize Professor Duan Xingwu’s medication rules from 102 cases of chronic urticaria patients from October to November 2015. Fifteen kinds of commonly used drugs were screened and rules in the herbal prescription are analyzed. Exploring Professor Duan’s clinical thoughts of “Disease differentiation and treatment” in treating chronic urticarial is to provide references for clinical treatment.