To observe the effect of dissolving phlegm-stasis on neurological function deficits，blood rheology，blood lipid and clinical efficacy in patients with ischemic stroke.Methods:Totally 120 patients with ischemic stroke were randomly divided into a control group (60 cases) and a study group (60 cases).The control group received conventional western medicine treatment，the study group Jiawei Huatan Huoxue decoction，additionally.All treated for 2 weeks.Neurological function deficits scores，blood rheology，blood lipids and clinical effects were compared.Results:After treatment，for the study group，the difference of neurological function deficits score was (9.05±1.16)，which was higher than that of control group of (5.25±0.79) (P<0.05); the level of whole blood viscosity，plasma viscosity，cholesterol and triglycerides were all lower than those of control group (P<0.05); the total effective rate was 91.67%，which was significantly higher than that of control group of 76.67% (P<0.05).Conclusion:Dissolving phlegm-stasis with Chinese medicine Jiawei Huatan Huoxue decoction is effective in the treatment of ischemic stroke，and is worthy of clinical use and promotion.