The observation of the clinical curative effect of Yiqiyangyinhuayujiedu Decoction on the treatment of PLGC with the deficiency of qi and yin with blood stagnation and toxin.Methods:There were 80 patients with PLGC，treated with modified Yiqiyangyinhuayujiedu Decoction as the basic.They were given 1 dose per day，two servings，for 3 months.The main symptoms and pathological changes of the patients before and after treatment were observed.Results:After treatment，the main symptom scores and the total score were significantly higher than before.The difference was statistically significant (P<0.01).After treatment，the main pathological changes，secondary pathological changes，main variable integral，secondary variable integral and total score of the variables were better than before treatment（P<0.05 or P<0.01）.In 80 cases，7 cases were markedly effective (8.75%)，59 cases effective (73.75%)，14 cases ineffective (17.50%)，and clinical total effective cases were 66 (82.50%).Conclusion:The Yiqiyangyinhuayujiedu Decoction has certain efficacy in main symptoms and pathology of PLGC with qi and yin deficiency with blood stagnation and toxin.