To observe the clinical effect and safety of the treatment of Jianpi Shengxue granule in selective orthopaedic surgical patients with preoperative anaemia. Methods:A total of 120 cases were randomly divided into two groups with 60 in each. The treatment group was treated with JianpiShengxue granule， while the control group was treated with iron succinate. The levels of hemoglobin(Hb) and serum ferritin(SF) before treatment， after 1w， 2w， 3w， 4w， sugary day， and after 1 d， 1 m， 2 m， 3 m were recorded. To compare the recovery duration， adverse reactions and prognosis of the two groups. Results:After treatment， Hb levels in both groups were improved， and the treatment group was better than the control group after 2w， 3w， and 4w of treatment (P<0.05). Besides， the waiting time of surgery of the treatment group was shortened by 6.35 days (P<0.05). In addition， SF recovery duration in the treatment group was shortened by 0.85 months (P<0.05). Also， the incidence of adverse reactions in the treatment group was significantly lower than that of the control group（P<0.05). Conclusion:Jianpi Shengxue granule can treat selective orthopaedic surgical patients with anaemia safely and effectively. It can shorten preoperative waiting time for surgery and SF level recovery time.